The long read sequencing market forecast is influenced by rapid technological progress in third-generation sequencing and the increasing incidence of genetic and rare diseases. AI plays a pivotal role in the sequencing process by enhancing data analysis speed and accuracy.
The report Long-Read Sequencing Market is expected to reach USD 3,129 million in 2029 from
USD 758 million in 2024, at a CAGR of 32.8% during the forecast period.
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398 Market Data Tables
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60
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306 Pages and in-depth TOC on " Long-Read
Sequencing Market - Global Forecast to 2029”
Some of the prominent key
players are:
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Oxford Nanopore Technologies
plc. (UK),
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PacBio (US),
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Illumina, Inc. (US),
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Agilent Technologies, Inc.
(US),
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Thermo Fisher Scientific
Inc. (US),
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10X Genomics, Inc. (US) and
many more......
Mergers & acquisitions,
investments & expansions, partnerships & collaborations, and new
product developments are some of the major strategies adopted by these key
players to enhance their positions in the Long-Read Sequencing Market.
DRIVER: Technological Advancement in genome sequencing
Dealing with the constraints of short-read sequencing technology,
long-read sequencing has grown important. The long-read sequencing has revealed
numerous underappreciated genomic characteristics including structural
variations and repetition arrays. Long-read sequencing enables investigation of
previously unreported genomic areas that were challenging to research, and
helps investigators to grasp the whole spectrum of human genetic variation.
Single-molecule real-time sequencing and nanopore-based sequencing are the two
primary forms of long-read sequencing technology. Developed by PacBio (US).
High-fi sequencing represents an advancement in SMRT sequencing with an
accuracy approaching 99.99%, HiFi sequencing provides sequence lengths of 10–20
kilobase pairs (kbp). This development has facilitated the identification of
structural variants and enabled the decoding of acrocentric short arms and
centromeres, two repeating sequences of the genome.
OPPORTUNITY: Rising demand for long-read sequencing in
clinical genomics
By allowing the identification of a wide spectrum of
genetic variants and fusion events, especially in illnesses like cancer,
long-read sequencing technology holds great potential in clinical genomics.
Long-read sequencing, unlike conventional short-read sequencing, can run in
real-time, therefore removing the requirement to batch samples. In urgent
clinical conditions and for employing fresh or fresh frozen samples, this
capacity is especially helpful. Long-read sequencing shines in detecting
important gene fusion events guiding therapy decisions in cancer diagnosis. In
chronic myeloid leukemia, for instance, Long-read sequencing finds the BCR-ABL
fusion protein—essential for focused treatments. More sensitive than short-read
sequencing techniques, long-read sequencing can identify structural variants
linked to treatment resistance, therefore enhancing the accuracy of illness
diagnosis and therapy monitoring.
Market Segmentation: -
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By offerings, the long-read
sequencing market is segmented into consumables, instruments, and services. The
consumables segment accounted for the largest share of the long-read sequencing
market in 2023. The large share of the consumables segment can be attributed to
the rising demand for genome sequencing, which is driving the consumption of
consumables for sequencing.
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By technology, the long-read
sequencing market is segmented into nanopore sequencing, single-molecule
real-time sequencing, and synthetic long-read sequencing. The nanopore
sequencing segment accounted for the largest share of the long-read sequencing
market in 2023.
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By workflow, the long-read
sequencing market is segmented into sequencing, sample preparation, and data
analysis. The sequencing segment accounted for the largest share in 2023. The
sequencing segment accounted for the largest share, as sequencing forms the
largest part of the workflow of the long-read sequencing market.
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By Application, the
long-read sequencing market is segmented into whole genome sequencing, targeted
sequencing, metagenomics, epigenetics, whole exome sequencing, and other
applications. In 2023, the whole genome sequencing segment accounted for the
largest share of the long-read sequencing market.
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By usage, the long-read
sequencing market is segmented into research and clinical. The research segment
accounted for the largest share of the long-read sequencing market in
2023.
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The long-read sequencing
market is segmented into six major regions, namely, North America, Europe, Asia
Pacific, Latin America, the Middle East, and Africa. North America is the
largest regional market for long-read sequencing in 2023, while Europe is the
second-largest market.
Recent Developments of Long Read Sequencing Industry.
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In May 2024, Oxford Nanopore Technologies
collaborated with Twist Bioscience to launch a new Pharmacogenomics Beta
Programme. This long-read pharmacogenomics solution, available for research
use, is designed to provide clear genetic results in a single end-to-end
workflow from sample to pharmacogenomics star allele call.
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In September 2023, PacBio announced a
partnership with Hamilton, Integra, Revvity, and Tecan to create fully
automated protocols to prepare samples for sequencing on Revio and Sequel II
and IIe systems.
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In March 2023, Illumina Inc. launched its
first product based on its novel Illumina Complete Long Read technology. The
high-performance, long-read, human whole-genome sequencing assay – Illumina
Complete Long Read Prep, Human – is compatible with Illumina NovaSeq X Plus,
NovaSeq X, and NovaSeq 6000 Sequencing Systems.
Growth in the long-read sequencing market
is mainly driven by the increased demand for whole genome sequencing backed by
human genome projects. The rising awareness of genome sequencing in disease
diagnosis and treatment is also supporting the market growth. Further, the
technological advancements in genome sequencing like increased accuracy and
read lengths are driving the growth. However, the high-cost investments to
develop long-read sequencing technologies are the major factors expected to
restrain the growth of this market to a certain extent.
Content Source: -
Long-Read
Sequencing Market Report
Long-Read
Sequencing Market Press Release